Tadalafil is a popular medication for erectile dysfunction (ED), commonly known by its brand name Cialis. While most men know tadalafil as a pill that helps with stronger and longer-lasting erections, many wonder: Does tadalafil also increase testosterone levels?
In this blog, we’ll explore the connection between tadalafil and testosterone, what research says, and whether men should rely on this pill for boosting hormone levels.
What Is Tadalafil?
Tadalafil is a medication that belongs to a group of drugs called PDE5 inhibitors. It helps relax blood vessels and improve blood flow to the penis, making it easier to achieve and maintain an erection.
Brand Name: Cialis
Available Strengths: 2.5 mg, 5 mg, 10 mg, 20 mg tablets
Duration: Can last up to 36 hours (why it’s nicknamed the “weekend pill”)
Unlike other ED pills like Viagra (sildenafil), tadalafil is also approved to treat benign prostatic hyperplasia (BPH) and sometimes pulmonary hypertension.
Understanding Testosterone
Testosterone is the primary male sex hormone. It plays a vital role in:
Sexual drive (libido)
Sperm production
Energy and muscle mass
Mood and mental well-being
Low testosterone (sometimes called Low T) can cause reduced sex drive, fatigue, depression, and difficulties with erections.
The Link Between Tadalafil and Testosterone
Now comes the big question: Does tadalafil increase testosterone?
Research suggests that tadalafil may indirectly improve testosterone levels in some men, but it is not a direct testosterone booster.
🔹 How It Might Work
Improved Erectile Function:
Men with ED often experience stress, anxiety, and lower sexual activity. By improving erections, tadalafil may help men have more frequent sexual activity, which can support natural testosterone production.Reduced Inflammation in the Prostate:
Some studies show tadalafil may help reduce prostate inflammation, which is linked to better hormone balance.Better Blood Flow and Testicular Function:
Since tadalafil improves circulation, it may help blood reach the testes, where testosterone is produced.
What Do Studies Say?
A clinical study found that men who took tadalafil daily for ED and prostate issues had a small but noticeable increase in testosterone levels compared to those who did not.
Another study suggested that the ratio of testosterone to estradiol (a form of estrogen) improved with tadalafil use, which may enhance overall male hormone balance.
However, these effects were modest and not enough to treat serious testosterone deficiency.
Can Tadalafil Replace Testosterone Therapy?
No. While tadalafil may help raise testosterone slightly, it is not a substitute for testosterone replacement therapy (TRT).
If a man has clinically low testosterone, a doctor may prescribe testosterone gels, injections, or patches.
Tadalafil can be used alongside TRT if needed for ED, but it should not be seen as a hormone treatment.
Benefits of Tadalafil Beyond Erections
Even if it doesn’t significantly boost testosterone, tadalafil provides many benefits for men’s health:
Helps achieve and maintain strong erections
Improves sexual confidence
Reduces urinary problems linked to enlarged prostate
Lasts up to 36 hours for more natural intimacy
Possible Side Effects of Tadalafil
Like all ED pills, tadalafil may cause side effects. Most are mild, but it’s important to be aware.
Common Side Effects:
Headache
Muscle aches
Back pain
Indigestion
Flushing
Serious Side Effects (rare):
Sudden vision or hearing loss
Chest pain
Prolonged erection (priapism) lasting more than 4 hours
Always consult a doctor before starting tadalafil.
Final Thoughts
So, does tadalafil increase testosterone?
Yes, but only slightly. Research shows that it can improve testosterone levels indirectly by enhancing sexual activity, improving prostate health, and supporting overall circulation.
No, it’s not a replacement for medical testosterone therapy if you have clinically low hormone levels.
In simple terms, tadalafil’s main role is to help with erections and sexual performance. Any testosterone boost is just a small added benefit.
If you’re concerned about low testosterone or erectile dysfunction, talk with your healthcare provider. They may recommend tadalafil, testosterone therapy, or a combination of both.
With a decade of experience in pharmaceutical research and medical writing, I specialize in exploring the science behind erectile dysfunction medications. My work emphasizes treatment innovation, safety evaluations, and patient-centric care strategies.